Prices verified October 2026
Arc-1 Compounded Tirzepatide + Glycine + B12

Compounded tirzepatide with glycine and B12 from Arc-1. Dose-tiered pricing: $199.99 (2.5 mg), $249.99 (5 mg), $399.99 (7.5 mg).

Arc-1 Compounded Tirzepatide Review

From $199.99
Our rating 4.0/5
Price: From $199.99  /  Form: Injectable  /  Doses: 2.5/5/7.5 mg  /  Extras: Glycine + B12

Arc-1 compounded tirzepatide review. Dose-tiered pricing from $199.99, glycine and B12 added, free consultation. Our editorial rating and full breakdown.

Transparent per-dose pricing on the product page
Free consultation and free shipping
LegitScript certified, 30-day guarantee
Higher starting price than BiltRx
Not available in CA, AR, IN, MN, SC
Key Features
  • Price (2.5 mg): $199.99
  • Price (5 mg): $249.99
  • Price (7.5 mg): $399.99
  • Form: Injectable only
  • Formulation: Tirzepatide + Glycine + B12 (10 mg / 5 mg / 500 mcg per mL)
  • Consultation: Free
  • Shipping: Free
  • Guarantee: 30-day money-back
  • Certification: LegitScript certified
  • Not available in: CA, AR, IN, MN, SC

The dose-tiered pricing is transparent and easy to compare. At 2.5 mg, Arc-1 costs $70.99 more per month than BiltRx's $129 compounded tirzepatide. At 5 mg the gap widens to $120.99. At 7.5 mg Arc-1 costs $270.99 more than BiltRx's listed price. However, Arc-1 bundles consultation and shipping into the listed price, while BiltRx charges those separately. The actual gap narrows once BiltRx's additional fees are factored in, though the exact amount depends on what BiltRx charges. See our BiltRx review for details on their pricing structure.

The jump from $249.99 at 5 mg to $399.99 at 7.5 mg is steep. That $150 increase for a single 2.5 mg dose increment may influence how long patients and prescribers choose to stay at the 5 mg level before escalating. Standard tirzepatide dosing goes up to 15 mg. Arc-1 does not list pricing for doses above 7.5 mg on its public pages, which leaves a question about what patients would pay at higher therapeutic doses.

What Is Inside
  • Active ingredient: Tirzepatide (compounded)
  • Glycine: 5 mg per mL
  • Vitamin B12: 500 mcg per mL
  • Concentration: 10 mg tirzepatide per mL
  • Form: Injectable solution

Arc-1 publishes more formulation detail than most competitors. The per-milliliter breakdown of each ingredient is listed upfront. This transparency is useful for patients and prescribers who want to know exactly what is in the vial.

Glycine at 5 mg per mL is a modest dose. Studies on glycine supplementation for metabolic health have used oral doses of 3 to 5 grams per day, which is orders of magnitude higher than what is present in this injection. The 500 mcg of B12 per injection represents roughly 200 times the recommended daily allowance, though B12 is water-soluble and excess is typically excreted. Neither additive is likely to cause harm at these doses. Whether they add therapeutic value in an injectable tirzepatide formulation is simply not established by evidence.

Check price at Arc-1 Sold and shipped by Arc-1. Price checked October 2026. We may earn a commission.

Arc-1 sells compounded tirzepatide in a formulation that adds glycine and vitamin B12 alongside the active peptide. Pricing scales with dose: $199.99 for 2.5 mg, $249.99 for 5 mg and $399.99 for 7.5 mg. The company includes free consultation, free shipping and a 30-day money-back guarantee with every order. Arc-1 holds LegitScript certification. It does not serve patients in California, Arkansas, Indiana, Minnesota or South Carolina. We evaluated the provider's public product data, pricing model and ordering experience to produce this assessment.

Arc-1 Compounded Tirzepatide Overview

Arc-1 positions itself as a telehealth provider that pairs licensed prescribers with a compounding pharmacy to deliver injectable tirzepatide. The formulation is not plain tirzepatide. Each milliliter contains 10 mg tirzepatide, 5 mg glycine and 500 mcg vitamin B12. This combination is specific to Arc-1 and differs from what most other compounded tirzepatide providers offer.

Glycine is an amino acid involved in collagen synthesis and neurotransmitter function. Vitamin B12 supports red blood cell formation and neurological function. Neither ingredient has been studied in a controlled trial specifically as an adjunct to tirzepatide for weight loss. Whether adding glycine and B12 to a tirzepatide injection provides meaningful clinical benefit beyond what tirzepatide alone delivers remains an open question with no published answer.

Arc-1 is LegitScript certified. LegitScript is a third-party verification service that evaluates online pharmacies and telehealth providers against regulatory standards. Certification means the company passed a review of its licensing, prescribing practices and pharmacy sourcing. It does not guarantee product quality at the vial level, but it does indicate that Arc-1 meets a baseline standard for legitimate telehealth operations.

How to Order and What to Expect

Arc-1 follows a straightforward telehealth ordering process. Patients complete an online health questionnaire and receive a free medical consultation with a licensed prescriber. The prescriber evaluates eligibility based on BMI, medical history and current medications. If approved, a prescription is written and sent to the compounding pharmacy.

Shipping is included in the price and the medication is delivered directly. The 30-day money-back guarantee provides a safety net for patients trying compounded tirzepatide for the first time. If a patient is unsatisfied within the first 30 days, they can request a refund. The specific terms of that guarantee should be confirmed directly with Arc-1 before ordering.

The state restriction is a meaningful limitation. Patients in California, Arkansas, Indiana, Minnesota and South Carolina cannot order from Arc-1. California alone accounts for roughly 12% of the US population. For patients in those states, BiltRx or other providers are the available options. Our brands page compares alternatives.

Like all tirzepatide prescriptions, patients should expect the standard dose escalation beginning at 2.5 mg. The prescriber determines the titration schedule based on clinical response and tolerability. Arc-1 lists pricing through 7.5 mg. Patients who require higher doses should ask during their consultation what those doses cost and whether the pharmacy can fill prescriptions at 10 mg, 12.5 mg or 15 mg.

Arc-1 Compounded Tirzepatide Summary
Product
Compounded tirzepatide + Glycine + B12 (injectable)
Price range
$199.99 (2.5 mg) to $399.99 (7.5 mg)
Consultation
Free
Shipping
Free
Guarantee
30-day money-back
Certification
LegitScript certified
State restrictions
Not available in CA, AR, IN, MN, SC
Editor Rating
4.0 / 5

Our Verdict

Arc-1 Compounded Tirzepatide receives an editorial rating of 4.0 out of 5. Sub-scores: Price 3.5, Convenience 4.2, Transparency 4.2, Support 4.0.

The transparency score is Arc-1's strongest suit alongside convenience. Published dose-tier pricing, a clearly stated formulation breakdown, LegitScript certification, free consultation and free shipping all contribute to a buying experience where patients know what they are getting before they commit. The 30-day guarantee reduces risk for first-time buyers and is something BiltRx does not offer.

The price score of 3.5 reflects the reality that Arc-1 is not cheap. Starting at $199.99 for the lowest dose and climbing to $399.99 at 7.5 mg, the cost accumulates quickly as patients titrate upward. Pricing above 7.5 mg is not listed, which creates uncertainty for patients who may need 10 mg or 15 mg to reach their weight loss goals. Compared to BiltRx at $129 per month, Arc-1 asks patients to pay a premium for its bundled services and enhanced formulation.

The convenience score of 4.2 reflects the free consultation, free shipping and straightforward ordering process. The state restriction knocks it down slightly. Five states excluded is a notable gap in coverage. The support score of 4.0 accounts for the money-back guarantee and responsive ordering experience, balanced against limited publicly available customer support documentation.

Arc-1 is best suited for patients who value pricing transparency, want a bundled all-in cost with no hidden fees, and are comfortable paying more for a LegitScript-certified provider with a satisfaction guarantee. Patients primarily driven by lowest possible monthly cost will find BiltRx more attractive. Neither product is FDA-approved. Patients in the five restricted states will need to look elsewhere. Our brands page lays out both options side by side.

Our rating

4.0out of 5 Rated by the Tirzepatide Reviews editorial team, October 2026
Price3.5
Convenience4.2
Transparency4.2
Support4.0

Compounded tirzepatide with glycine and B12 from Arc-1. Dose-tiered pricing: $199.99 (2.5 mg), $249.99 (5 mg), $399.99 (7.5 mg).

Transparent per-dose pricing on the product page
Free consultation and free shipping
LegitScript certified, 30-day guarantee
Higher starting price than BiltRx
Not available in CA, AR, IN, MN, SC
Editorial rating: our own assessment against the criteria on this site.

FAQ - Arc-1 Compounded Tirzepatide

Is Arc-1 compounded tirzepatide FDA-approved?

No. Compounded tirzepatide from Arc-1 is not FDA-approved. The addition of glycine and B12 to the formulation has not been evaluated by the FDA. The only FDA-approved tirzepatide products are Mounjaro (for type 2 diabetes) and Zepbound (for chronic weight management). LegitScript certification verifies that Arc-1 operates as a legitimate telehealth provider, but it does not constitute FDA approval of the compounded product itself.

Why does Arc-1 add glycine and B12 to tirzepatide?

Arc-1 includes 5 mg glycine and 500 mcg vitamin B12 per milliliter in its compounded tirzepatide formulation. Glycine is an amino acid associated with metabolic and neurological functions. B12 supports red blood cell production and energy metabolism. No published clinical trial has tested this specific combination as a weight loss treatment. Whether these additions provide measurable benefit beyond tirzepatide alone is not supported by peer-reviewed evidence at this time.

Can I order Arc-1 if I live in California?

No. Arc-1 does not serve patients in California, Arkansas, Indiana, Minnesota or South Carolina. These restrictions are typically related to state-level telehealth regulations or compounding pharmacy licensing requirements. Patients in those states can consider BiltRx, which lists no state restrictions, or seek a local prescriber who works with a compounding pharmacy licensed in their state.

What happens if I need a dose higher than 7.5 mg?

Arc-1 publishes pricing through 7.5 mg ($399.99). The standard tirzepatide dose escalation goes up to 15 mg. Arc-1 does not list prices for 10 mg, 12.5 mg or 15 mg on its public pages. Patients who anticipate needing higher doses should ask about pricing and availability during their consultation before starting treatment. If higher doses are not available or are prohibitively expensive, switching providers at that stage would require a new consultation and potentially a gap in supply.

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